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Fansimef buy in Agege
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Fansimef

Fansimef

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Nigeria, Agege
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Description
The components of FANSIMEF® are complementary. For instance, between sulfadoxine and pyrimethamine,the active ingredients of the well known antimalarial FANSIMEF® there is pronounced mutual potentiation (synergism), while mefloquine, a highly potent erythrocytic schizonticide, has an additive effect when combined with sulfadoxine-pyrimethamine. Compared with the individual ingredients, the combination of active substances contained in FANSIMEF® considerably delays emergence of resistance in rodent malaria models. The resistance-delaying property of FANSIMEF® is of great importance in view of the ability of the antimalaria pathogens in man, in particular Plasmodium Falciparum, to develop resistance to antimalarial drugs relatively quickly.

The central action of FANSIMEF® in malaria therapy consists in killing the asexual erythrocytic forms of the malaria pathogen. FANSIMEF® is also effective against malaria parasites which have developed resistance to other antimalarials such as chloroquine and other 4 -aminoquinoline derivatives, proguanil, pyrimethamine and sulfonamide-pyrimethamine combinations.
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